Lymphocyte Subpopulation Analysis in Cerebrospinal Fluid (CSF) by Immunoassay

Why This Test Is Done

Your doctor may order this test if you have symptoms like headaches, neck stiffness, confusion, or neurological issues that could involve the brain or spinal cord. It’s often used to check for infections, inflammation, or other conditions affecting the CSF, such as multiple sclerosis, meningitis, or certain cancers.

What to Expect Before the Test

You’ll likely have a lumbar puncture (spinal tap) where a small needle is inserted into your lower back to collect CSF. The procedure is usually quick and may cause mild discomfort. You may be asked to lie still for a short time afterward.

What the Test Results Mean

The test looks at different types of lymphocytes (a type of white blood cell) in your CSF, such as T-cells, B-cells, or natural killer cells. Abnormal levels can indicate infections, autoimmune diseases, or other neurological conditions. Your doctor will interpret the results in the context of your symptoms and medical history.

Common Conditions This Test Helps Diagnose

This test can help diagnose or monitor conditions like meningitis, encephalitis, multiple sclerosis, lymphoma, or other neurological disorders that affect the immune cells in the CSF.