Skip to content

Lymphocyte and Monocyte Count from Whole Blood (with White Blood Cell Differential)

Published: August 9, 2026Updated: August 16, 2026

This test measures the proportions of different white blood cell types in your blood, specifically focusing on lymphocytes and monocytes. It helps assess immune function and inflammation.

Quick summary

["This test helps identify immune system balance and potential infections or inflammatory conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30119-2
Short code
Lymphs IgM # WBC
Synonyms
Lymphs IgM # WBC
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85004
SNOMED
900000000000003002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Your Health

Your immune system relies on various white blood cells (WBCs) to fight infections and maintain health. This test provides a detailed breakdown of your WBC types, including lymphocytes (a key part of your immune response) and monocytes (which help fight chronic infections and inflammation).

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a small needle inserted into your arm to draw a small amount of blood. The process usually takes a few minutes. If you’re on blood thinners or have a history of bleeding issues, let your provider know before the test.

How the Results Are Used

Healthcare providers use these results to diagnose or monitor conditions like immune deficiencies, infections, autoimmune diseases, or certain cancers. For example, low lymphocyte counts might suggest weakened immunity, while abnormal monocyte levels could indicate chronic inflammation.

Common Conditions This Test Helps Detect

This test can help identify issues such as leukemia, lymphoma, HIV/AIDS (due to low lymphocyte counts), chronic infections, or inflammatory diseases like rheumatoid arthritis. It may also be used to monitor treatment responses in certain conditions.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: How Results May Affect Your Care

Short name

WBC Differential (Lympho/Monocyte Focus)

Frequently asked questions

How might abnormal results change my treatment plan?
If your results show unusual proportions of lymphocytes or monocytes, your healthcare provider may recommend further testing, adjustments to medications, or lifestyle changes. For instance, low lymphocyte counts might lead to immune-boosting therapies or monitoring for infections more closely.
What if my results are outside the normal range?
If your results are outside the normal range, your provider will discuss them with you during your follow-up visit. They may ask you to return for additional testing or to monitor changes over time. The exact meaning depends on your overall health and medical history.
Can I eat or drink before this test?
You can eat and drink normally before this test, as no special diet or fasting is required. However, always follow your provider’s instructions for any specific preparations related to your condition.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy