Skip to content

Lymphocyte and Monocyte Blood Count (with Differential Analysis)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of lymphocytes and monocytes in your blood, which helps assess immune function and identify potential infections, inflammation, or blood disorders.

Quick summary

["This blood test helps doctors understand how your immune system is working and spot possible health issues early."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35081-9
Short code
Lymphs+Monos # Bld
Synonyms
Lymphs+Monos # Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Are Lymphocytes and Monocytes?

Lymphocytes are a type of white blood cell that plays a key role in fighting infections and diseases. Monocytes are another type of white blood cell that helps remove debris and pathogens from your body. Both are part of your immune system and can be measured to check for health concerns.

Why Might This Test Be Ordered?

Your doctor may order this test to evaluate your immune response, diagnose conditions like infections, autoimmune diseases, or blood disorders, or monitor treatments for conditions affecting white blood cells.

How Is the Test Performed?

A small blood sample is taken from a vein in your arm. The sample is then analyzed in a lab to count and identify the different types of white blood cells, including lymphocytes and monocytes.

What Do the Results Mean?

Results show the absolute counts of lymphocytes and monocytes. Abnormal levels may indicate infections, immune system disorders, or other health issues. Your doctor will interpret the results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Changes in lymphocyte or monocyte counts can signal underlying health problems. For example, low lymphocyte counts might suggest immune deficiencies or chronic illnesses, while high levels could indicate acute infections or certain inflammatory conditions. This test helps guide treatment decisions and monitor disease progression.

Short name

Lympho/Monocyte Blood Test

Frequently asked questions

What does a low or high count of lymphocytes or monocytes mean?
A low count of either cell type may suggest weakened immunity, infections, or certain medications. A high count could indicate an active infection, inflammation, or other immune responses. Your doctor will discuss these findings with you.
How long does it take to get the results of this test?
Results are typically available within a few days, depending on lab processing times. Your doctor will contact you once the results are ready.
Can lifestyle changes affect these test results?
Yes, stress, illness, or certain medications can temporarily affect white blood cell counts. If you’re taking medications or have recent health changes, let your doctor know before the test.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy