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Peripheral Blood Smear with Lymphocyte Count (Qualitative and Quantitative Analysis)

Published: August 9, 2026Updated: August 16, 2026

This test examines your blood sample under a microscope to check the number and appearance of white blood cells, specifically lymphocytes, which help fight infections.

Quick summary

["Assesses immune cell health and infection risk through microscopic and quantitative analysis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
60473-6
Short code
Lymphs Vac Bld Ql Smear
Synonyms
Lymphs Vac Bld Ql Smear
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test to diagnose or monitor conditions affecting your immune system, such as infections, autoimmune diseases, or blood disorders. It can also help evaluate whether treatments are working or if you need further medical attention.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. If you’re concerned about discomfort, let your healthcare provider know. Avoid eating or drinking for 2–3 hours before the test if instructed.

What Happens During the Test

Blood is collected in a tube and sent to the lab. A technician spreads a thin layer on a microscope slide for examination. Some tests may also measure lymphocyte counts automatically using specialized equipment.

What the Results Mean

Results show the types and numbers of white blood cells, including lymphocytes. Abnormal counts may indicate infections, immune disorders, or other health issues. Your doctor will interpret results in the context of your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lymphocyte smear

Frequently asked questions

How might abnormal findings affect my health?
Low lymphocyte counts may suggest immune deficiencies, severe infections, or certain cancers. High counts could indicate chronic infections, inflammation, or overactive immune responses. Always discuss results with your doctor for personalized guidance.
What if I have a history of blood disorders?
Your doctor may use this test to track changes in your condition, assess treatment effectiveness, or identify new problems. If you have a history of blood disorders, they may also order additional tests for comparison.
Can I eat or drink after the test?
Typically, you can resume normal activities immediately after the blood draw. However, avoid strenuous exercise for 24 hours to prevent bruising or excessive bleeding at the site.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy