Lymphocyte T-Cell Receptor Gamma/Delta and Alpha/Beta Subunit Gene Rearrangement Panel
A molecular panel evaluates T-cell receptor gene patterns for clonality, helping assess suspected T-cell lymphoproliferative disorders.
["This panel looks for clonal T-cell patterns that may support evaluation of an abnormal lymphocyte population."]
Key facts at a glance
- LOINC
- 80718-0
- Short code
- Lymph TCR gam delt + alpha beta sub Pnl
- Synonyms
- Lymph TCR gam delt + alpha beta sub Pnl
- Category
- liver
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This panel examines the rearrangement of T-cell receptor gamma/delta and alpha/beta genes. It can show whether a population of T lymphocytes has a consistent, or clonal, pattern.
Why might I need this test?
It may be used when an abnormal T-cell population is suspected, particularly in the evaluation of a possible T-cell lymphoproliferative disorder. Results are interpreted together with symptoms, physical findings, imaging, and other laboratory or tissue studies.
How is the test performed?
DNA from the submitted specimen is analyzed with a molecular method to compare the T-cell receptor gene patterns. The specimen may be blood or tissue, depending on the clinical question and the laboratory’s testing instructions.
How do I prepare for the test?
No special preparation is usually needed for a blood sample, but follow the laboratory’s instructions. For a tissue sample, collection is performed by a healthcare professional and may require a biopsy or other procedure.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A clonal pattern may support the presence of an abnormal T-cell population, including a possible lymphoproliferative disorder. However, clonality does not by itself establish cancer, and a nonclonal result does not completely exclude a T-cell disorder; results must be interpreted in the full clinical context.
Short name
T-cell receptor gene rearrangement panel
Frequently asked questions
Does a clonal result mean I have cancer?
What sample is needed for this test?
Can this test replace a biopsy?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy