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Blood smear examination for white blood cell morphology (lymphocyte count and differential analysis)

Published: August 9, 2026Updated: August 16, 2026

This test examines the appearance and proportions of white blood cells in your blood sample, focusing on lymphocytes, which are a type of immune cell. It helps assess immune function and identify abnormalities.

Quick summary

["A blood smear review can detect infections, immune disorders, or blood diseases by examining cell shapes and counts."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93953-8
Short code
Lymph Villous Bld Ql Smear
Synonyms
Lymph Villous Bld Ql Smear
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to evaluate your immune system, diagnose infections (such as viral or bacterial), or check for conditions like leukemia, lymphoma, or other blood disorders. It’s also used to monitor treatment responses in certain diseases.

What to Expect Before the Test

No special preparation is needed. A simple blood draw from your arm is all that’s required. The sample is then examined under a microscope by a trained lab professional.

What the Test Results Mean

Results typically show the types and proportions of white blood cells (e.g., lymphocytes, neutrophils, eosinophils). Abnormal counts or shapes may indicate infections, immune disorders, or other health issues. Your provider will interpret these findings in the context of your overall health.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions like chronic infections, autoimmune diseases, or blood cancers. For example, high lymphocyte counts might suggest a viral infection or certain cancers, while unusual cell shapes could point to disorders like leukemia.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

WBC smear review

Frequently asked questions

How long will I need to wait for my results?
Results are usually available within 1 to 3 business days, depending on lab workload. Your provider will contact you once they’re ready.
Can I eat or drink before this test?
No dietary restrictions apply. You can eat and drink normally before the blood draw.
Is there any risk or discomfort with this test?
Minimal discomfort is possible during the blood draw, such as a slight pinch or sting. Rarely, bruising or swelling may occur at the site. Most people tolerate it well.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy