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Lysine concentration (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lysine, an essential amino acid, in your blood. Lysine helps with protein synthesis, calcium absorption, and immune function.

Quick summary

["Lysine levels can help assess nutritional status or identify potential deficiencies."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13404-9
Short code
Lysine Amn-mCnc
Synonyms
Lysine Amn-mCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like muscle weakness, fatigue, or if you have a condition that affects protein metabolism, such as kidney disease or certain infections. It may also be used to monitor nutritional support or evaluate dietary needs.

What Does the Result Mean?

Results are not typically provided in absolute numbers for this specific test, as reference ranges can vary by lab and may not be widely standardized. Your provider will interpret the result in the context of your overall health and symptoms.

Common Reasons for Testing

Lysine levels are less commonly tested than other amino acids because lysine is naturally abundant in foods like meat, dairy, and legumes. However, it may be checked in specialized cases, such as evaluating protein deficiency or monitoring patients on specific diets or medical treatments.

Sample Collection and Preparation

A blood sample is typically drawn from a vein in your arm. The sample is collected in a tube and sent to the lab for analysis. No special preparation is usually required, but fasting may be advised depending on the clinical context.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lysine Level

Frequently asked questions

What Are Normal Results?
There are no widely standardized reference ranges for lysine in serum or plasma due to its abundance in the body and diet. Your healthcare provider will use clinical judgment to assess if results are within expected ranges for your situation.
Can Lysine Levels Be Low or High?
Extremely low lysine levels may suggest severe malnutrition, certain metabolic disorders, or malabsorption issues. High levels are less common and may require further evaluation to rule out lab errors or unusual conditions.
How Often Should This Test Be Done?
This test is not routinely performed unless there is a specific clinical indication. Your provider will determine the need for repeat testing based on your health status and symptoms.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy