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Lysine concentration in serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lysine, an essential amino acid, in your blood serum. Lysine helps support immune function, muscle growth, and calcium absorption.

Quick summary

["Lysine levels can help diagnose or monitor conditions affecting amino acid metabolism or kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27107-2
Short code
Lysine Amn-sCnc
Synonyms
Lysine Amn-sCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like muscle weakness, fatigue, or kidney issues, or if you’re being evaluated for metabolic disorders or nutritional deficiencies. It may also be part of a broader evaluation for conditions like Hartnup disease or other aminoacidopathies.

What to Expect Before the Test

No special preparation is typically needed. You may be asked to fast for a few hours before the blood draw, but this depends on your provider’s instructions. Bring any medications you’re currently taking to your appointment.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. The process is quick and usually painless. You may feel a slight pinch or discomfort, but it shouldn’t last long.

What the Results Mean

Results are compared to a general reference range for healthy adults. Abnormally low or high levels may signal underlying health concerns, such as kidney disease, liver problems, or certain genetic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Lysine Level

Frequently asked questions

What causes low lysine levels?
Low lysine levels can result from kidney disease, genetic disorders like Hartnup disease, malnutrition, or certain medications that interfere with amino acid metabolism. Lifestyle factors, such as poor diet, may also play a role.
What should I do if my lysine level is low?
If your provider identifies low lysine levels, they may recommend dietary changes (such as increasing lysine-rich foods like meat, fish, and dairy) or supplements under medical supervision. Follow their guidance closely to avoid complications.
Can I adjust my diet before this test?
Generally, no specific dietary restrictions are required for this test, but avoid extreme changes to your usual diet unless advised by your provider. If you have kidney issues, check with them first to ensure safe dietary adjustments.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy