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Lysine concentration in serum/plasma (mass concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lysine, an essential amino acid, in your blood. Lysine helps with muscle repair, calcium absorption, and immune function.

Quick summary

["Lysine supports muscle health and immune function; low levels may indicate certain medical conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13375-1
Short code
Lysine CSF-mCnc
Synonyms
Lysine CSF-mCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like muscle weakness, poor wound healing, or conditions linked to amino acid imbalances. It could also be part of a broader evaluation for metabolic disorders or nutritional deficiencies.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have fasting instructions depending on your provider, but lysine levels are generally stable without dietary restrictions. Bring any medications or supplements you take regularly to your appointment.

What the Results Mean

Results are compared to a general reference range for healthy adults. While specific ranges vary by lab, low lysine levels may suggest dietary deficiencies, certain metabolic disorders, or kidney issues. High levels could indicate liver disease or other metabolic conditions.

Common Conditions Linked to Lysine Levels

Lysine is often checked in patients with suspected amino acid disorders, severe malnutrition, or those undergoing dialysis. It may also be monitored in people with chronic kidney disease or those on certain medications that affect amino acid metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lysine Level

Frequently asked questions

What questions might you have about this test?
This test is typically used as part of a broader evaluation rather than a standalone diagnostic tool. If your results are outside the expected range, your provider will discuss next steps, such as dietary changes, further testing, or treatment options.
Do I need to fast before this test?
Fasting may not be required for lysine testing, but always follow your healthcare provider’s instructions. Some labs may ask for fasting if the test is part of a metabolic panel, but lysine itself is not affected by recent food intake.
Can lifestyle changes affect lysine levels?
Yes, diet plays a role. Foods high in lysine (such as meat, fish, legumes, and dairy) can influence results. If you suspect dietary deficiencies, discuss dietary adjustments with your provider before interpreting test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy