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Lysine concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lysine, an essential amino acid, in your blood. Lysine helps with protein synthesis, immune function, and calcium absorption.

Quick summary

["Lysine levels can be checked if you have symptoms of amino acid imbalances or certain medical conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47693-7
Short code
Lysine SFr SerPl
Synonyms
Lysine SFr SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like muscle weakness, skin rashes, or unusual fatigue. It could also be part of a broader evaluation for metabolic disorders or nutritional deficiencies, especially in cases involving protein metabolism or kidney function.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw. Wear loose clothing and plan to rest for a short time afterward, as you might feel lightheaded.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. The process is quick and typically painless. The blood sample will be sent to a lab for analysis.

What the Results Mean

Results will show the concentration of lysine in your blood. While reference ranges vary by lab, abnormal levels may suggest conditions like amino acid disorders, kidney disease, or malnutrition. Your provider will interpret results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Lysine levels can be important in diagnosing or monitoring certain metabolic conditions, such as lysosomal storage disorders or aminoacidopathies. Low levels may indicate malnutrition or malabsorption, while elevated levels could be linked to kidney issues or certain genetic disorders. Always discuss results with your healthcare provider for personalized insights.

Short name

Lysine Level

Frequently asked questions

What causes low or high lysine levels?
Low lysine levels may be due to poor nutrition, digestive issues, or certain genetic disorders that affect amino acid metabolism. High levels could result from kidney problems or overproduction of lysine in the body, though this is less common.
Can lifestyle changes affect lysine levels?
Yes, diet plays a key role. Foods high in protein, such as meat, dairy, and legumes, contain lysine. If you suspect dietary deficiencies, talk to your doctor about dietary adjustments or supplements, but never self-treat without professional guidance.
Is this test often done as part of a routine checkup?
No, this test is usually not part of a standard routine checkup. It’s typically ordered based on specific symptoms, medical history, or concerns about amino acid metabolism or kidney function.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy