Skip to content

Lipoprotein(a) [Lp(a)] concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of lipoprotein(a), a type of cholesterol-related protein that may increase your risk of heart disease.

Quick summary

["Lipoprotein(a) is linked to higher cardiovascular risks and may require monitoring or treatment depending on your health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
79567-4
Short code
LysoPC(26:0) DBS LC/MS/MS-sCnc
Synonyms
LysoPC(26:0) DBS LC/MS/MS-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
lc-ms-ms
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). While it shares similarities with LDL (low-density lipoprotein), it behaves differently in the body and is associated with a higher risk of clotting and heart disease. Elevated levels may be detected even if your overall cholesterol is normal.

Why Might You Need This Test?

Your doctor may order this test if you have a family history of heart disease, stroke, or early-onset cardiovascular issues, or if you have other risk factors like high blood pressure or diabetes. It’s also sometimes checked in people with certain genetic conditions or those undergoing preventive screening.

How Is the Test Performed?

A small blood sample is drawn from your arm, typically in a clinic or lab. The sample is processed and analyzed to measure the concentration of lipoprotein(a) in your blood.

What Do Results Mean?

Results are reported as a numerical value representing the concentration of lipoprotein(a) in milligrams per deciliter (mg/dL). While there are no universally accepted reference ranges for everyone, higher levels may indicate increased cardiovascular risk, prompting further evaluation or lifestyle changes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lipoprotein(a)

Frequently asked questions

How often will I need this test?
This test is often ordered as part of a cardiovascular risk assessment, but frequency depends on your doctor’s recommendations. If you have a history of high lipoprotein(a) levels, your doctor may suggest monitoring it periodically, possibly every few years or as needed for treatment adjustments.
What are the normal ranges?
There are no strict universal normal ranges for lipoprotein(a) because levels vary by individual. Your doctor will interpret your results in the context of your overall health, family history, and other risk factors. Very high levels may require additional testing or treatment strategies.
Can lifestyle changes affect lipoprotein(a) levels?
While lifestyle factors like diet, exercise, and smoking can influence other cholesterol types, lipoprotein(a) levels are generally more resistant to changes from diet or exercise alone. However, some medications (like statins) may help lower it, so talk to your doctor about personalized approaches.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy