Skip to content

Cholesterol (Total) – Mass Concentration in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of cholesterol in your blood, an important part of your lipid profile that helps assess heart health.

Quick summary

["Cholesterol levels influence your risk for cardiovascular disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90923-4
Short code
LysoPC(26:0) DBS-mCnc
Synonyms
LysoPC(26:0) DBS-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to evaluate your risk for heart disease, monitor existing heart conditions, or check for high cholesterol levels that could lead to plaque buildup in your arteries. It’s often part of a broader lipid panel that also includes other fats like triglycerides and HDL cholesterol.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 9–12 hours before the test if it’s part of a lipid panel. If you’re unsure, ask your provider. Blood is drawn from a vein in your arm, and you may feel a slight pinch, but it usually doesn’t cause discomfort afterward.

What the Results Mean

Cholesterol results are typically reported as a single number (total cholesterol) and are used alongside other lipid measurements to guide treatment decisions. While specific ranges vary by lab, high levels may signal a need for lifestyle changes or medication to lower cholesterol.

Common Causes of Abnormal Results

High cholesterol can result from diet, genetics, obesity, or certain medical conditions like diabetes or hypothyroidism. Low levels may occur with liver disease or certain medications. Your provider will discuss these findings with you based on your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Cholesterol

Frequently asked questions

How often will I need this test?
The frequency depends on your health status. Healthy adults may get it every 4–6 years, while those with risk factors (like high blood pressure or a family history of heart disease) may need it more often, every 1–2 years.
What if my cholesterol is too high?
If your results show high cholesterol, your provider may recommend dietary changes (like reducing saturated fats), exercise, or medications like statins to lower it. You’ll work together to create a plan tailored to your needs.
Does diet affect this test?
Yes, diet plays a major role. Eating foods high in saturated fats (like red meat or fried foods) can raise cholesterol, while fruits, vegetables, and whole grains may help lower it. Ask your provider for personalized dietary advice.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy