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Lipoprotein(a) concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of lipoprotein(a), a type of cholesterol-related protein that may increase your risk of heart disease or blood clots.

Quick summary

["Lipoprotein(a) levels may help assess cardiovascular risk beyond traditional cholesterol measures."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
79322-4
Short code
LysoPC(26:0) SerPl-sCnc
Synonyms
LysoPC(26:0) SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have a family history of heart disease, early-onset coronary artery disease, or certain genetic conditions. It may also be used in people with high cholesterol or those undergoing heart disease prevention strategies.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from your arm in a clinic or lab. Avoid eating or drinking for at least 8–12 hours before if fasting is required (check with your provider).

How the Test Works

Blood is drawn and analyzed using a specialized immunoassay method to measure lipoprotein(a) concentration, which reflects the amount of this protein in your bloodstream.

What the Results Mean

Results are compared to general reference ranges, though individual ranges may vary. High levels may signal increased cardiovascular risk, prompting further evaluation or lifestyle adjustments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lp(a) Lipoprotein(a)

Frequently asked questions

What causes lipoprotein(a) levels to be high?
High lipoprotein(a) levels can be influenced by genetics (inherited from family members) and may also be affected by certain medical conditions, medications, or lifestyle factors like smoking or obesity. Some research suggests diet and exercise may have limited impact on levels, but further study is ongoing.
How often should I get this test?
Your doctor will determine how often you need this test based on your individual risk factors, medical history, and overall health. It may be part of routine cardiovascular screening or monitoring, especially if you have a family history of elevated levels or related conditions.
Can lifestyle changes lower lipoprotein(a) levels?
While lifestyle changes like diet, exercise, and smoking cessation may help manage other cardiovascular risk factors, there is limited evidence that they significantly lower lipoprotein(a) levels. Genetic factors play a major role, and treatments like medications may be recommended for very high levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy