Skip to content

24-Hour Urinary Lysozyme Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of lysozyme, a protein that helps fight infections, in your urine over a 24-hour period.

Quick summary

["Helps assess urinary lysozyme levels for potential infection or inflammatory conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34335-0
Short code
Lysozyme 24h Ur-mCnc
Synonyms
Lysozyme 24h Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
20
Ref high
400
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82670
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like frequent urinary tract infections (UTIs), kidney issues, or if you’re being evaluated for conditions like lysosomal storage disorders or certain inflammatory diseases. It can also help monitor treatment responses in some cases.

What to Expect Before the Test

You’ll need to collect all urine for 24 hours, typically starting after midnight on one day and ending midnight the next. Drink plenty of fluids to help urine flow, but avoid certain medications (like some antibiotics) without consulting your doctor. A urine collection kit will be provided.

How the Test Works

The collected urine is analyzed in a lab to measure lysozyme levels. This involves separating and quantifying the protein using advanced techniques like mass spectrometry or immunoassay, depending on the lab’s method.

What the Results Mean

Results are reported as the total mass of lysozyme excreted in urine over 24 hours. Elevated levels may suggest conditions like chronic urinary tract inflammation, certain genetic disorders, or immune system abnormalities. Lower-than-expected levels might indicate rare metabolic issues.

Reference range

Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24h Urinary Lysozyme

Frequently asked questions

What causes lysozyme levels to be high?
High urinary lysozyme levels may be linked to chronic urinary tract infections, inflammation, or certain genetic disorders. Your doctor will consider your symptoms, medical history, and other test results to determine the cause.
What if my results are outside the expected range?
If your results are outside the expected range, your healthcare provider will discuss them with you. They may recommend further testing, adjustments to treatment, or additional evaluations to understand what’s happening in your body.
Can diet or medications affect this test?
Yes, certain medications (like some antibiotics) and dietary factors (like high fluid intake) can influence urine volume and lysozyme excretion. Always follow your doctor’s instructions about diet, medications, and collection procedures to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy