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24-Hour Urinary Lysozyme Excretion Rate

Published: August 9, 2026Updated: August 16, 2026

This test measures how much lysozyme, a protein that helps fight infections, appears in your urine over 24 hours. It may be used to check for conditions like tuberculosis or certain inflammatory diseases.

Quick summary

["This test helps assess urinary lysozyme levels over a full day to identify potential infections or immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2590-8
Short code
Lysozyme 24h Ur-mRate
Synonyms
Lysozyme 24h Ur-mRate
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
20
Ref high
400
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82670
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like persistent cough, fever, or unexplained weight loss, or if you’ve been diagnosed with conditions like tuberculosis (TB) or other infections that affect the immune system. It can also help monitor certain immune-related diseases.

What Does the Test Involve?

You’ll collect all urine for a full 24-hour period in a special container. The sample is then sent to a lab for analysis. This method ensures accurate measurement of lysozyme over time.

What to Expect Before the Test

No special preparation is needed, but drink plenty of fluids to help your urine flow normally. Avoid taking any medications that might affect urine composition unless instructed otherwise.

What to Expect During the Test

You’ll need to collect every drop of urine for 24 hours, including at night. Use a clean container and label it properly. Some clinics may provide a 24-hour urine collection kit to simplify the process.

Reference range

Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lysozyme Urine Rate

Frequently asked questions

What causes lysozyme to appear in urine?
Lysozyme in urine can be elevated due to infections (like tuberculosis), inflammatory conditions, or certain immune system disorders. It may also appear in response to stress or other immune responses, though this is less common.
How long does it take to get results?
Results are typically available within 1 to 2 weeks after the lab processes your sample, depending on the lab’s workflow and any follow-up testing required.
Can I take medications before the test?
Avoid taking medications that might alter urine composition unless your provider specifically approves it. Always check with your healthcare team before starting or stopping any medications.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy