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Serum Lysozyme Concentration (Substance Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lysozyme, a protein that helps fight bacterial infections, in your blood serum. Lysozyme is produced by white blood cells and other tissues.

Quick summary

["Lysozyme helps defend your body against harmful bacteria and may be checked if you have an infection or certain inflammatory conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54019-5
Short code
Lysozyme Ab Ser Ql
Synonyms
Lysozyme Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does Lysozyme Do in Your Body?

Lysozyme is an enzyme that plays a role in breaking down bacterial cell walls. It’s naturally found in tears, saliva, and white blood cells, where it helps prevent infections. In blood tests, lysozyme levels can sometimes be elevated in response to infections, autoimmune diseases, or certain inflammatory processes.

When Might You Need This Test?

Your healthcare provider may order a lysozyme test if you have symptoms like frequent infections, unexplained fevers, or signs of inflammation. It may also be used in research or specialized diagnostic contexts, such as evaluating conditions like chronic granulomatous disease or certain immune disorders.

Common Reasons for Testing

While lysozyme testing isn’t as common as other blood tests, it may be part of a broader evaluation when doctors suspect conditions affecting immune function or bacterial susceptibility. For example, it could be considered in cases of recurrent infections or when other tests point toward an underlying immune issue.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate the serum (the liquid part without clots) for testing. The lysozyme level is measured using a specialized laboratory method, often an immunoassay or enzymatic technique, to detect its presence and concentration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lysozyme Level

Frequently asked questions

Is lysozyme testing covered by insurance?
Whether your test is covered depends on your insurance plan, the reason for testing, and whether your healthcare provider has documented medical necessity. Some insurance companies may require prior authorization for specialized or less common tests like lysozyme. Always check with your insurance provider or healthcare team for specifics.
What are typical reference ranges for lysozyme?
Reference ranges for lysozyme can vary by lab and method. Since lysozyme levels can fluctuate based on health status, infection, or other factors, your results will be interpreted in the context of your clinical picture rather than a single numeric range. Your doctor will discuss what your results mean for you.
Can lysozyme levels change with diet or lifestyle?
Diet and lifestyle factors generally do not significantly affect lysozyme levels in blood. However, infections, inflammation, or certain medications (like some antibiotics or immune-modulating drugs) may influence results. If you’re concerned about how your health habits might impact test results, talk to your doctor.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy