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Lysozyme, Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lysozyme, an enzyme made mainly by certain white blood cells, in your blood. It can help evaluate conditions that affect white blood cells and immune function.

Quick summary

["A lysozyme blood level gives your doctor a clue about white blood cell activity and can support the evaluation of certain blood and immune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11182-3
Short code
Lysozyme IgE Qn
Synonyms
Lysozyme IgE Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Lysozyme?

Lysozyme is an enzyme that helps break down parts of bacterial cell walls and is part of the body's natural defense system. It is produced mainly by neutrophils and macrophages, which are types of white blood cells. Measuring lysozyme in the blood can reflect how active these cells are.

Why Your Doctor Ordered This Test

Your doctor may order a lysozyme test when evaluating a suspected problem with white blood cells or the immune system. It is sometimes used as one piece of information when investigating certain blood cancers or inflammatory conditions. Results are always interpreted alongside your symptoms, exam, and other tests.

How the Test Is Done

The test usually requires a blood sample drawn from a vein in your arm. The sample is sent to a laboratory, where the level of lysozyme is measured. No special preparation is typically needed unless your care team instructs otherwise.

What the Results Mean

A lysozyme level that is higher or lower than expected can point toward certain conditions, but it is not a diagnosis by itself. Your doctor will consider the result together with other blood tests and your overall health picture. Ask your care team to explain what your specific result means for you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Lysozyme measurement can support the evaluation of conditions involving white blood cell activity, such as certain leukemias, and may be used in assessing inflammatory or immune-related disorders. Because results are nonspecific, they are interpreted with other laboratory and clinical findings rather than used alone.

Short name

Lysozyme

Frequently asked questions

Do I need to fast before a lysozyme blood test?
Fasting is usually not required for this test. Follow any specific instructions your care team gives you, since preparation can depend on what other tests are being done at the same time.
Can a lysozyme result diagnose a disease on its own?
No. A lysozyme level is one piece of information and is not a diagnosis by itself. Your doctor interprets it together with your symptoms, physical exam, and other test results.
What happens if my lysozyme level is abnormal?
An abnormal result may prompt your doctor to recommend additional tests to understand the cause. It does not automatically mean you have a serious condition, and your care team will explain the next steps for your situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy