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: Lysozyme, IgG4, Mass Concentration, Measurement

Published: August 9, 2026Updated: August 16, 2026

: This is a laboratory measurement that combines assessment of lysozyme and immunoglobulin G4 (IgG4) in a specimen, reported as a mass concentration. It is used to help evaluate certain inflammatory and immune-related conditions.

Quick summary

[": Lysozyme and IgG4 testing can support evaluation of specific immune and inflammatory disorders, but results must be interpreted by a clinician in context."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97956-7
Short code
Lysozyme IgG4-mCnc
Synonyms
Lysozyme IgG4-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What Is Being Measured

: The test measures the amount of lysozyme and immunoglobulin G4 (IgG4) present in the sample, expressed as a mass concentration. Lysozyme is an enzyme produced by certain immune cells, and IgG4 is a subtype of antibody involved in immune responses.

: Why It May Be Ordered

: A clinician may order this testing to help investigate conditions associated with abnormal immune cell activity or elevated IgG4-related disease. It is typically part of a broader evaluation rather than a stand-alone diagnostic test.

: How the Test Is Performed

: A blood or other appropriate specimen is collected and sent to a laboratory, where specialized methods measure the concentration of each analyte. The exact method used depends on the performing laboratory.

: How to Interpret Results

: Results are reported as concentrations and should be compared with the reference intervals provided by the performing laboratory. Because values can be affected by many factors, interpretation requires clinical context and sometimes additional testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: Lysozyme and IgG4 measurements can be useful supportive markers in the evaluation of immune-mediated and inflammatory conditions, including IgG4-related disease. However, they are not diagnostic on their own, and results should always be interpreted alongside symptoms, physical examination, imaging, and other laboratory findings.

Short name

: NONE

Frequently asked questions

: Does this test diagnose a specific disease?
: No. It provides supportive information and must be interpreted together with other clinical and laboratory findings.
: Do I need to fast before this test?
: Fasting requirements vary by laboratory and clinical context. Follow the instructions provided by your healthcare provider or the testing laboratory.
: Can medications affect the results?
: Some medications and underlying conditions may influence immune markers. Tell your healthcare provider about all medications and supplements you are taking.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy