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Lymphocyte Count (Serum or Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of lymphocytes, a type of white blood cell that helps fight infections and supports immune function. Lymphocytes include B cells, T cells, and natural killer cells.

Quick summary

["Lymphocytes help protect your body from illness and infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108836-8
Short code
Lysozyme Msmt SerPl
Synonyms
Lysozyme Msmt SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is a Lymphocyte Count Used For?

A lymphocyte count may be checked to evaluate your immune system. It can help diagnose or monitor conditions like infections, autoimmune diseases, or certain cancers. Your doctor might also order this test to assess how well your immune response is working after treatments like chemotherapy.

How Is This Test Done?

A small amount of blood is drawn from a vein in your arm. The blood is then sent to a lab where it is analyzed to count the lymphocytes. No special preparation is usually needed, but you may be asked to avoid certain medications or activities for a short time before the test.

What Does a Lymphocyte Count Tell You?

A lymphocyte count can show whether your immune system is functioning normally. Low levels may indicate immune suppression, infections, or certain diseases, while high levels could suggest overactive immune responses or conditions like chronic inflammation.

When Might You Need This Test?

Your doctor may recommend a lymphocyte count if you have symptoms like frequent infections, unexplained weight loss, fatigue, or if you’re undergoing treatment for a condition that affects the immune system.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Lymphocyte counts can play a key role in diagnosing and managing immune-related disorders. For example, low lymphocyte counts might be seen in HIV/AIDS, certain cancers, or after organ transplants. High counts could be linked to conditions like lupus or certain infections.

Short name

Lymphocyte Level

Frequently asked questions

Why might my doctor order a lymphocyte count?
Your doctor might order this test to check your immune health, especially if you have symptoms like frequent infections, fatigue, or if you’re receiving treatments that affect your immune system.
What are the typical reference ranges for lymphocyte counts?
Reference ranges can vary by lab and individual health. Your doctor will provide your specific results and explain what they mean in the context of your health.
Can lifestyle changes affect my lymphocyte count?
Yes, factors like diet, stress, sleep, and certain medications can influence your immune cells. Maintaining good health habits may support your immune system, but your doctor should interpret results based on your overall health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy