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: Lysozyme, Serum or Plasma, by Liquid Chromatography

Published: August 9, 2026Updated: August 16, 2026

: This test measures the amount of lysozyme, an enzyme produced mainly by certain white blood cells, in your serum or plasma. It can help your doctor evaluate conditions that affect these immune cells.

Quick summary

[": A lysozyme blood test gives your care team information about certain white blood cell activity and helps support the evaluation of related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
4665-6
Short code
Lysozyme SerPl-cCnc
Synonyms
Lysozyme SerPl-cCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What Is Being Measured?

: Lysozyme is an enzyme found in many body fluids and produced in large amounts by certain white blood cells called monocytes and macrophages. Measuring its level in serum or plasma can provide clues about how active these cells are.

: Why Your Doctor May Order It

: Your doctor may order a lysozyme test as part of the work-up for conditions that involve these white blood cells, such as certain blood cell disorders or inflammatory conditions. It is usually interpreted alongside other blood tests and your overall clinical picture.

: How the Test Is Done

: A small blood sample is collected from a vein in your arm and sent to the laboratory. The laboratory measures lysozyme concentration using a chromatographic method (liquid chromatography).

: What the Results Mean

: Results are reported as a concentration in your serum or plasma and are compared with the laboratory's reference interval. Levels outside the expected range may prompt further testing; your doctor will interpret the result together with your symptoms and other findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: Lysozyme (Serum/Plasma)

Frequently asked questions

: Do I need to fast before this test?
: Fasting requirements vary by laboratory and by the tests ordered with it. Follow the instructions given by your healthcare provider or the collection site.
: Can I get the result from a home test?
: This measurement is typically performed on a blood sample collected by a healthcare professional and analyzed in a laboratory. Discuss any home testing options with your provider.
: What if my result is outside the reference range?
: A result outside the reference range does not by itself mean you have a disease. Your doctor will consider it alongside your symptoms, medical history, and other test results to decide whether further evaluation is needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy