Lysozyme, Serum or Plasma, Mass Concentration
This test measures the amount of lysozyme, an enzyme produced mainly by certain white blood cells, in your serum or plasma. It can help evaluate conditions associated with increased white cell activity or kidney involvement.
["A serum lysozyme measurement reflects levels of an enzyme made by white blood cells and can support evaluation of certain blood and kidney conditions."]
Key facts at a glance
- LOINC
- 2589-0
- Short code
- Lysozyme SerPl-mCnc
- Synonyms
- Lysozyme SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Lysozyme?
Lysozyme is an enzyme found in many body fluids and tissues. It is produced in large amounts by neutrophils and macrophages, which are types of white blood cells, and it helps break down bacterial cell walls as part of the body's defenses. Measuring lysozyme in blood gives information about how active these cells are.
Why the Test Is Ordered
A clinician may order this test to help investigate conditions in which white blood cells are increased or abnormally active, or to help assess certain kidney and immune system disorders. It is usually interpreted alongside other blood counts, chemistry tests, and clinical findings rather than on its own.
How the Sample Is Collected
A small blood sample is drawn from a vein, typically in your arm, and the serum or plasma is separated for testing. The measurement is reported as a mass concentration, meaning the amount of lysozyme by weight per volume of sample. No special preparation is usually needed unless your care team says otherwise.
Understanding Your Results
Results are reported as a concentration and must be compared with the laboratory's own reference interval, because values can vary between labs and methods. Levels may be higher or lower in different conditions, and a single result is rarely diagnostic. Your clinician will interpret it together with your symptoms and other test results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Serum Lysozyme
Frequently asked questions
Does an abnormal lysozyme level mean I have a serious disease?
Do I need to fast before a serum lysozyme test?
Can medications or other conditions affect the result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy