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Lysozyme, Serum or Plasma, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lysozyme, an enzyme produced mainly by certain white blood cells, in your serum or plasma. It can help evaluate conditions associated with increased white cell activity or kidney involvement.

Quick summary

["A serum lysozyme measurement reflects levels of an enzyme made by white blood cells and can support evaluation of certain blood and kidney conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2589-0
Short code
Lysozyme SerPl-mCnc
Synonyms
Lysozyme SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Lysozyme?

Lysozyme is an enzyme found in many body fluids and tissues. It is produced in large amounts by neutrophils and macrophages, which are types of white blood cells, and it helps break down bacterial cell walls as part of the body's defenses. Measuring lysozyme in blood gives information about how active these cells are.

Why the Test Is Ordered

A clinician may order this test to help investigate conditions in which white blood cells are increased or abnormally active, or to help assess certain kidney and immune system disorders. It is usually interpreted alongside other blood counts, chemistry tests, and clinical findings rather than on its own.

How the Sample Is Collected

A small blood sample is drawn from a vein, typically in your arm, and the serum or plasma is separated for testing. The measurement is reported as a mass concentration, meaning the amount of lysozyme by weight per volume of sample. No special preparation is usually needed unless your care team says otherwise.

Understanding Your Results

Results are reported as a concentration and must be compared with the laboratory's own reference interval, because values can vary between labs and methods. Levels may be higher or lower in different conditions, and a single result is rarely diagnostic. Your clinician will interpret it together with your symptoms and other test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Lysozyme

Frequently asked questions

Does an abnormal lysozyme level mean I have a serious disease?
Not necessarily. Lysozyme levels can change for many reasons, and an abnormal result is not a diagnosis by itself. Your clinician will consider it together with your symptoms, physical exam, and other laboratory findings.
Do I need to fast before a serum lysozyme test?
Fasting is generally not required for this test unless your care team instructs otherwise. Follow any specific preparation instructions given by your clinician or the laboratory.
Can medications or other conditions affect the result?
Yes. Various illnesses and some treatments can influence white blood cell activity and lysozyme levels. Tell your clinician about all medications and health conditions so the result can be interpreted correctly.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy