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Serum Lysozyme Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lysozyme, a protein produced by white blood cells, in your blood serum. Lysozyme helps protect your body from bacterial infections.

Quick summary

["Lysozyme may be checked if you have symptoms of infection or certain immune-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6289-3
Short code
Lysozyme SerPl-sCnc
Synonyms
Lysozyme SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does Lysozyme Do in Your Body?

Lysozyme is an enzyme found naturally in tears, saliva, and white blood cells. It plays a role in breaking down bacterial cell walls, helping your body fight off infections. High levels may suggest an active immune response, while very low levels could indicate immune system dysfunction or certain genetic disorders.

Why Might Your Doctor Order This Test?

Your doctor may order a lysozyme test if you have symptoms like frequent infections, skin rashes, or unexplained fevers. It can also be part of evaluating conditions such as chronic granulomatous disease or other immune deficiencies.

Sample Collection and Preparation

A blood sample is taken from a vein, usually in your arm. The blood is then processed to separate the serum (the liquid part after clotting). This serum is sent to a lab for testing. You may be asked to fast before the test, but this is not always required.

Test Results Interpretation

Results are reported as a concentration level of lysozyme in the serum. Interpretation depends on clinical context, including your medical history and symptoms. Your doctor will discuss the results with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lysozyme (Serum)

Frequently asked questions

What Does Lysozyme Level Mean for My Health?
Elevated lysozyme levels may indicate an active infection, inflammation, or certain immune disorders. Low levels could suggest immune system issues, such as chronic granulomatous disease or other genetic conditions affecting white blood cell function. Always discuss your results with your healthcare provider.
How Often Should I Get This Test?
The frequency of this test depends on your medical condition and treatment plan. Your doctor will determine if and when to repeat the test based on your symptoms and lab results.
What Are Common Causes of Abnormal Results?
Abnormal lysozyme levels can be caused by infections, autoimmune diseases, or genetic disorders. Chronic infections, certain medications, or other health conditions may also affect lysozyme levels. Always consult your doctor for personalized reasons.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy