Lysosomal enzyme activity in serum (e.g., β-glucosidase or other lysosomal hydrolase activity)
This test measures the activity of enzymes found in lysosomes, tiny cell structures that break down waste materials. It may be used to diagnose or monitor conditions affecting lysosomal function.
["This test helps assess lysosomal enzyme activity, which can indicate genetic disorders or other conditions affecting cellular waste processing."]
Key facts at a glance
- LOINC
- 17232-0
- Short code
- Lysozyme Tear-cCnc
- Synonyms
- Lysozyme Tear-cCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may order this test if you have symptoms or a family history suggestive of lysosomal storage disorders (e.g., mucopolysaccharidoses, Gaucher disease, or Niemann-Pick disease). It may also be used in research or specialized diagnostic evaluations.
What to Expect Before the Test
No special preparation is typically required, but you may be asked to fast for a few hours before the blood draw if instructed by your provider. Bring any medications or supplements you’re taking to discuss with your doctor.
How the Test Works
A small blood sample is drawn from a vein in your arm. The sample is tested for enzyme activity in a lab setting, often using a biochemical method like enzymatic assays to measure breakdown rates of specific substrates.
What the Results Mean
Results may show elevated or reduced enzyme activity compared to expected levels, which can help identify lysosomal disorders. Your doctor will interpret results in the context of your symptoms, medical history, and other tests.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal enzyme activity can signal lysosomal storage disorders, where waste materials accumulate inside cells due to missing or defective enzymes. Early diagnosis is crucial for managing symptoms and planning treatment options, such as enzyme replacement therapy.
Short name
Lysosomal Enzyme Activity
Frequently asked questions
What causes lysosomal enzyme activity to be tested?
What symptoms might lead to this test?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy