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Amylase (Plasma or Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of amylase, an enzyme produced by the salivary glands and pancreas that helps break down carbohydrates. High levels may indicate inflammation or damage in these organs.

Quick summary

["Amylase helps digest food, but elevated levels often signal underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55204-2
Short code
Macroamylase Plr Ql
Synonyms
Macroamylase Plr Ql
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order an amylase test to check for conditions affecting the pancreas, such as pancreatitis, or to evaluate salivary gland issues like sialadenitis. It can also help diagnose other conditions like kidney disease or certain infections.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into a vein in your arm for blood collection. If your specimen is plasma, it may be drawn from a different vein or processed from whole blood immediately.

What Happens During the Test?

A healthcare professional will take a blood sample from your arm. The sample is then sent to a lab for analysis. Results are typically available within a few days.

What the Results Mean

Amylase levels can vary based on factors like diet, hydration, and medications. Elevated levels may suggest pancreatitis, salivary gland disorders, or other conditions. Lower-than-normal levels might indicate pancreatic insufficiency or other metabolic issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Amylase Level

Frequently asked questions

What causes amylase levels to be high?
Common causes include pancreatitis (inflammation of the pancreas), salivary gland infections or blockages (like sialadenitis), kidney problems, or certain medications. Rarely, it may be linked to heart attacks or other conditions.
What causes amylase levels to be low?
Low amylase levels can occur with chronic pancreatitis, pancreatic insufficiency, or certain genetic disorders affecting enzyme production. Other rare causes may include liver disease or severe malnutrition.
Do I need to avoid certain foods before this test?
No specific diet restrictions apply, but inform your doctor about any medications you’re taking, as some may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy