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Macrophages, Body Fluid, Manual Count

Published: August 9, 2026Updated: August 16, 2026

This test counts macrophages in a sample of body fluid by manual microscopic examination. Macrophages are immune cells that help clear debris and fight infection, and their numbers can help your care team evaluate inflammation or other conditions.

Quick summary

A manual macrophage count in body fluid helps assess the immune cell response in the sampled fluid.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71628-2
Short code
Macrophages NFr.DF Prt Manual
Synonyms
Macrophages NFr.DF Prt Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

A laboratory professional examines a prepared slide of your body fluid under a microscope and counts the macrophages present. Macrophages are a type of white blood cell that engulf and break down debris, microbes, and other particles. The result is usually reported as part of a white blood cell differential for the fluid.

Why It May Be Ordered

Your healthcare provider may order this test when fluid has collected in a body cavity, such as the chest, abdomen, or around the heart or joints, and they want to understand what kind of cells are present. The macrophage count can support evaluation of inflammation, infection, or other causes of fluid buildup.

How the Sample Is Collected

A small sample of the fluid is collected by a procedure your provider performs, such as a needle draw from the affected area. The sample is sent to the laboratory, where it is prepared and reviewed manually. Your provider will explain the collection procedure and any preparation needed.

What the Results Mean

Results are interpreted together with other findings from the same fluid sample and with your symptoms, imaging, and history. No single cell count gives a diagnosis on its own, so your provider will explain what the findings mean for your situation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Macrophage counts in body fluid are used alongside other cell counts and fluid characteristics to help distinguish between types of inflammation and to guide further testing. They are not diagnostic by themselves, and results should always be interpreted in the full clinical context.

Short name

Body Fluid Macrophages

Frequently asked questions

Does this test diagnose a condition on its own?
No. The macrophage count is one piece of information that your provider combines with other test results, symptoms, and imaging to reach a conclusion.
Is the procedure to collect the fluid painful?
Fluid collection involves a needle, so you may feel brief discomfort or pressure. Your care team will take steps to keep you comfortable and will explain the procedure beforehand.
How long does it take to get results?
Because the slide is reviewed manually, turnaround time varies by laboratory. Ask your provider or the laboratory about the expected timeframe for your results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy