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Macrophage Count in Body Fluids

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of macrophages present in a sample of body fluid, which helps assess immune cell activity and potential inflammation or infection.

Quick summary

["Understanding macrophage levels in fluids can guide treatment for immune-related conditions or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30427-9
Short code
Macrophages NFr Fld
Synonyms
Macrophages NFr Fld
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to evaluate immune responses, check for infections (such as abscesses or certain cancers), or monitor conditions like chronic inflammation or autoimmune diseases. It can also help diagnose or monitor diseases affecting macrophage function, such as certain infections or immune disorders.

How Is the Sample Collected?

A healthcare provider will collect a sample of body fluid, such as blood plasma, serum, or another fluid like cerebrospinal fluid or synovial fluid, depending on the clinical indication. The sample is then sent to a lab for analysis.

What Does the Test Result Mean?

Results are typically reported as a count of macrophages per unit volume of fluid. Elevated levels may indicate an active immune response or infection, while very low levels could suggest immune suppression or certain diseases. Interpretation depends on clinical context and other test results.

Common Conditions Monitored or Diagnosed

This test may be used to diagnose or monitor conditions like localized infections (e.g., abscesses), certain cancers (e.g., lymphoma), chronic inflammatory diseases, or immune system dysfunctions. It can also help assess the body’s response to treatments targeting macrophages.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Macrophage Fluid Count

Frequently asked questions

What does a high macrophage count in body fluids usually indicate?
A high macrophage count may suggest an ongoing immune response, such as chronic inflammation, an infection (like tuberculosis or certain abscesses), or a reaction to certain medications or treatments that stimulate macrophage activity.
What does a low macrophage count in body fluids typically mean?
A low macrophage count could indicate immune suppression, certain cancers (e.g., leukemia), or systemic diseases that impair macrophage function. It may also occur in patients receiving immunosuppressive therapies.
Is this test painful or uncomfortable for the patient?
The procedure for collecting the fluid sample may involve minor discomfort, such as a needle stick or slight pressure, depending on the type of fluid collected. Most patients report it as mild and temporary, similar to a routine blood draw.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy