Serum Prolactin Level (Mass Fraction)
This test measures the amount of prolactin, a hormone produced by the pituitary gland, in your blood. Prolactin helps regulate breast milk production and affects other bodily functions.
["Prolactin levels can indicate potential hormonal imbalances or conditions affecting your pituitary gland."]
Key facts at a glance
- LOINC
- 72575-4
- Short code
- Macroprolactin/Prolactin MFr.DF SerPl
- Synonyms
- Macroprolactin/Prolactin MFr.DF SerPl
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 2
- Ref high
- 18
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84146
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Might You Need This Test?
Your healthcare provider may order a prolactin test if you have symptoms like irregular menstrual periods, infertility, breast changes, headaches, or signs of a pituitary tumor. It can also help diagnose conditions like hyperprolactinemia or evaluate certain medications that may affect hormone levels.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to avoid certain medications or activities that could influence results, such as smoking or certain supplements. You’ll typically have blood drawn from a vein in your arm.
What the Results Mean
Results help determine if your prolactin levels are within the expected range or if they’re elevated or low, which could signal underlying health concerns. Your doctor will discuss these findings in the context of your symptoms and medical history.
Common Reasons for Testing
This test is often used to diagnose conditions like pituitary tumors, hyperprolactinemia (high prolactin levels), or to check for hormonal imbalances that may affect fertility, menstrual cycles, or other bodily functions.
Reference range
Adult males: 2-18 ng/mL; Females: 2-29 ng/mLN/A
For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Prolactin
Frequently asked questions
How Often Do I Need This Test?
What Are Normal Results?
Can Diet or Lifestyle Affect Results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy