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Serum Prolactin Level (Mass Fraction)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of prolactin, a hormone produced by the pituitary gland, in your blood. Prolactin helps regulate breast milk production and affects other bodily functions.

Quick summary

["Prolactin levels can indicate potential hormonal imbalances or conditions affecting your pituitary gland."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72575-4
Short code
Macroprolactin/Prolactin MFr.DF SerPl
Synonyms
Macroprolactin/Prolactin MFr.DF SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2
Ref high
18
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84146
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your healthcare provider may order a prolactin test if you have symptoms like irregular menstrual periods, infertility, breast changes, headaches, or signs of a pituitary tumor. It can also help diagnose conditions like hyperprolactinemia or evaluate certain medications that may affect hormone levels.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to avoid certain medications or activities that could influence results, such as smoking or certain supplements. You’ll typically have blood drawn from a vein in your arm.

What the Results Mean

Results help determine if your prolactin levels are within the expected range or if they’re elevated or low, which could signal underlying health concerns. Your doctor will discuss these findings in the context of your symptoms and medical history.

Common Reasons for Testing

This test is often used to diagnose conditions like pituitary tumors, hyperprolactinemia (high prolactin levels), or to check for hormonal imbalances that may affect fertility, menstrual cycles, or other bodily functions.

Reference range

Adult males: 2-18 ng/mL; Females: 2-29 ng/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Prolactin

Frequently asked questions

How Often Do I Need This Test?
The frequency depends on your symptoms, medical history, and treatment plan. Your doctor will determine how often you need follow-up tests based on your specific situation.
What Are Normal Results?
There are no specific numeric reference ranges provided here, as they can vary by lab and individual factors. Your doctor will interpret results in relation to your health status and needs.
Can Diet or Lifestyle Affect Results?
Some activities, like exercise, stress, or certain medications, can temporarily affect prolactin levels. Avoiding these factors before testing can help ensure more accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy