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Mass concentration of uric acid in plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of uric acid, a natural substance produced when your body breaks down certain foods and substances, including purines found in meat and seafood. High levels may suggest conditions like gout or kidney issues.

Quick summary

["Uric acid levels help diagnose or monitor conditions affecting your metabolism or kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31184-5
Short code
MAK Ur-mCnc
Synonyms
MAK Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like joint pain (especially in big toes), frequent kidney problems, or if you’re at risk for gout or kidney stones. It may also be part of routine check-ups for people with certain health conditions.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a metabolic panel. Bring any medications you’re currently taking to your appointment.

How the Test Works

A blood sample is drawn from a vein in your arm. The blood is sent to a lab where it’s analyzed to measure uric acid levels using a specialized method, often high-performance liquid chromatography (HPLC).

What the Results Mean

Results are compared to a general reference range, but exact values can vary by lab. High levels may indicate overproduction of uric acid or impaired kidney function, while low levels are less commonly evaluated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Uric Acid Plasma Level

Frequently asked questions

What causes high uric acid levels?
High uric acid can result from diet (rich in purines), kidney problems, certain medications, or genetic factors. Lifestyle factors like alcohol consumption or obesity may also play a role.
How can I lower my uric acid levels?
Dietary changes (reducing red meat, seafood, and sugary drinks), staying hydrated, and maintaining a healthy weight can help. Your doctor may also recommend medications if needed.
How often should I get this test?
Your provider will determine frequency based on your health status. Regular monitoring may be needed if you have a history of gout, kidney disease, or other metabolic conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy