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24-Hour Urinary Manganese Excretion Rate

Published: August 9, 2026Updated: August 16, 2026

This test measures how much manganese your body excretes in urine over a 24-hour period. Manganese is a mineral that plays a role in metabolism, but high levels can indicate exposure or health concerns.

Quick summary

["Assesses manganese metabolism and potential exposure risks through urine output over a full day."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
8203-2
Short code
Manganese 24h Ur-mRate
Synonyms
Manganese 24h Ur-mRate
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
20
Ref high
400
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82670
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like neurological issues, liver problems, or signs of manganese toxicity. It’s also used in research or occupational health settings to monitor exposure to manganese, often found in certain industrial jobs or from environmental sources.

What to Expect Before the Test

No special preparation is needed beyond collecting your urine over a full 24-hour period. You’ll typically start and end the collection at the same time each day, storing the urine in a container until it’s sent to the lab.

How the Test Works

The lab analyzes the total manganese content in your collected urine sample. This helps determine your body’s excretion rate, which can reflect how your kidneys and metabolism handle manganese.

Possible Results and Interpretation

Results are usually reported as the amount of manganese excreted per day (e.g., micrograms or milligrams). Your provider will compare these results to what’s considered normal for your body and context, such as exposure history or symptoms.

Reference range

Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Manganese Urine Rate

Frequently asked questions

What causes elevated manganese levels in urine?
Elevated manganese excretion can result from occupational exposure (e.g., welding, mining), certain medications, or environmental sources like contaminated water. Chronic exposure may lead to health problems over time.
How long does it take to get results?
Results typically arrive within 1–3 business days, depending on lab processing times. Your provider will contact you once they’re ready to discuss the findings.
Can diet affect this test?
Dietary manganese intake is usually low enough to not significantly impact this test, but avoid consuming large amounts of manganese-rich foods (e.g., nuts, chocolate) during your collection period if instructed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy