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Manganese/Creatinine [Mass Ratio], 24-Hour Urine

Published: August 9, 2026Updated: August 16, 2026

A 24-hour urine test that measures manganese excretion and may adjust the result using urine creatinine to account for urine concentration.

Quick summary

["This test can help evaluate recent exposure to manganese, including exposure from supplements, food, or the workplace."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29935-4
Short code
Manganese/Creat 24h Ur
Synonyms
Manganese/Creat 24h Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Manganese is a trace mineral needed in small amounts for normal body function. This test measures how much manganese is removed in urine collected over 24 hours. Creatinine may be used to help account for variations in urine concentration.

Why might I need this test?

The test may be ordered to assess recent exposure to manganese from occupational sources, supplements, or unusually high dietary intake. It may also be used to follow certain health conditions or treatments involving manganese.

How is the test performed?

You collect all urine for a full 24-hour period in the container provided by the laboratory. The sample is then analyzed for manganese, and the laboratory may also measure creatinine to calculate the reported result.

How do I prepare for the test?

Follow the laboratory's collection instructions exactly, including when to start and how to store the container. Record any missed collections and tell the clinician about manganese-containing supplements, medicines, and possible workplace exposure; do not stop supplements or treatments without medical advice.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-hour urine manganese

Frequently asked questions

What does an elevated urine manganese result mean?
It may suggest that you have had increased exposure to manganese or are absorbing more than usual. Your clinician will consider your occupation, supplements, medications, symptoms, and other tests when interpreting it.
Why is a 24-hour urine collection needed?
Collecting all urine for 24 hours provides a more complete estimate of how much manganese your body is eliminating than a single urine sample. Missed collections can make the result less reliable.
Should I stop taking supplements before this test?
Do not stop any supplement or medication unless your healthcare professional tells you to. Tell the laboratory about relevant supplements because manganese exposure can affect the result.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy