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Manganese, Serum Concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of manganese, a trace mineral, present in your blood serum. Manganese is involved in various metabolic processes, including energy production and bone formation.

Quick summary

["Understanding your manganese levels can help assess potential deficiencies or excesses that may affect health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
104848-7
Short code
Manganese IgE RAST
Synonyms
Manganese IgE RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may recommend this test if you have symptoms like fatigue, neurological issues, or conditions linked to manganese imbalance, such as liver disease or certain genetic disorders. It may also be part of a broader evaluation for metabolic or mineral disorders.

What Does the Test Involve?

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum, which is sent to a lab for analysis using a specialized method, often immunoassay or similar techniques.

What Are Common Causes of Abnormal Results?

Low manganese levels might result from poor diet, certain medications, or malabsorption issues. High levels could be due to exposure to manganese from environmental sources (e.g., industrial settings) or certain medical conditions affecting metabolism.

What Do Results Typically Mean?

Interpreting results requires a healthcare provider’s guidance. While manganese is essential in tiny amounts, both deficiencies and excesses can impact health differently depending on the context of your symptoms and medical history.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Manganese

Frequently asked questions

How often do I need this test?
This test is usually not a routine screening unless you have specific symptoms or risk factors. Your provider will determine if monitoring is needed based on your health status and medical history.
What are the typical reference ranges for this test?
Reference ranges for manganese levels can vary by lab and method. They are not widely standardized, so your results should always be discussed with your healthcare provider.
Can lifestyle changes affect manganese levels?
Yes, diet, exposure to environmental manganese, and certain medications can influence manganese levels. Discuss dietary habits and potential exposures with your provider to understand how they may impact your results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy