Skip to content

24-Hour Manganese Intake Assessment

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of manganese consumed over a 24-hour period, often used to evaluate dietary exposure or absorption in clinical or research settings.

Quick summary

["This helps assess how much manganese you’re ingesting daily."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
81007-7
Short code
Manganese intake 24h Est
Synonyms
Manganese intake 24h Est
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
20
Ref high
400
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
estimated
CPT
82670
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have suspected manganese toxicity (e.g., from occupational exposure, certain medications, or dietary concerns), or if you’re part of a study investigating dietary mineral absorption. It can also be used in research or specialized clinical scenarios to monitor long-term exposure levels.

What to Expect Before the Test

No special preparation is typically required. You’ll provide a 24-hour urine collection, starting from one point in time (often midnight or noon) and continuing until the same time the next day. Follow your provider’s instructions carefully to ensure accurate results.

How the Test Works

Your urine sample is analyzed to determine the total manganese content over the 24-hour period. The test does not measure manganese levels in your blood or tissues but focuses on dietary intake through urine excretion.

What the Results Mean

Results are expressed in units of mass concentration (e.g., micrograms per day). Higher than expected values may indicate excessive manganese intake, while lower values could suggest insufficient exposure or dietary restrictions.

Reference range

Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Chronic manganese exposure at high levels can lead to health issues such as neurological problems, liver or kidney damage, or other organ toxicity. This test helps identify potential over-exposure, guiding further evaluation or dietary adjustments if needed. It is less commonly used than blood manganese tests but is valuable in specific research or occupational health contexts.

Short name

Manganese Intake (24h)

Frequently asked questions

What does a high manganese intake mean?
A high manganese intake may signal excessive exposure, potentially from dietary sources, supplements, or occupational hazards. Your provider may review your diet, medications, or work environment to determine the cause and recommend changes if necessary.
How is this different from a blood manganese test?
This test measures manganese intake through urine excretion over 24 hours, reflecting dietary absorption. A blood test measures current manganese levels in your bloodstream, which can indicate recent exposure or body stores. Both are useful but serve different purposes in assessment.
Can I change my diet before this test?
Yes, if your provider suggests it, you may need to follow a specific diet or avoid certain foods to ensure accurate results. Always follow their instructions to avoid interfering with the test’s validity.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy