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Manganese, Serum, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of manganese in a sample of serum, the liquid part of blood. It can help assess exposure to manganese, a trace mineral that is essential in small amounts but can be harmful in excess.

Quick summary

["A serum manganese test estimates how much manganese is present in the liquid portion of your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87467-7
Short code
Manganese Spec-mCnc
Synonyms
Manganese Spec-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Manganese Is and Why It Matters

Manganese is a trace mineral that your body needs in very small amounts to support normal functions such as bone formation and metabolism. It is found in many foods and in some occupational and environmental settings. While small amounts are necessary, too much manganese over time can build up in the body and affect the nervous system.

How the Test Works

The test measures the mass concentration of manganese in serum, meaning the amount of manganese per volume of the liquid portion of your blood. A small blood sample is collected and analyzed in a laboratory. Because manganese is present at very low levels, laboratories use specialized techniques to measure it accurately.

Reasons Your Doctor May Order It

Your doctor may order this test if you have possible exposure to manganese, such as through certain workplace environments, welding, mining, or industrial processes. It may also be used when someone has symptoms that could relate to manganese excess, or to monitor people with known exposure. Interpretation always depends on your history, symptoms, and other test results.

What Results Can Mean

Results are compared with the laboratory's own reference interval, because ranges vary between labs and methods. A value outside the expected range does not by itself confirm or rule out a health problem. Your doctor will consider the result together with your exposures, symptoms, and other tests, and may recommend repeat or additional testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Manganese

Frequently asked questions

Does an abnormal result mean I have a health problem?
Not necessarily. A result outside the reference range can be affected by exposure, diet, other conditions, or laboratory factors. Your doctor will interpret it alongside your history, symptoms, and other tests before drawing conclusions.
Do I need to prepare for this test?
Preparation depends on the laboratory and your doctor's instructions. Follow any specific directions you are given. Because manganese can be influenced by contamination and other factors, let your healthcare team know about any supplements or unusual exposures.
Can this test tell me my exact exposure level?
A single blood test gives an estimate at the time of collection and may not reflect long-term exposure or body stores. Your doctor may use it together with your exposure history and other evaluations to build a fuller picture.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy