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Manganese concentration (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of manganese, a trace mineral, present in your blood. Manganese is essential for various bodily functions but can become harmful in excess.

Quick summary

["Knowing your manganese levels helps assess potential exposure risks or metabolic health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5684-6
Short code
Manganese Ur-mCnc
Synonyms
Manganese Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like neurological issues (e.g., tremors, memory problems), liver or kidney problems, or if you’ve been exposed to manganese through occupational hazards (e.g., mining, welding) or environmental sources (e.g., certain industrial chemicals). They might also order it to monitor long-term conditions like Wilson’s disease or to check for metabolic disorders.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours if the test involves a blood draw. Wear comfortable clothing and arrive with your ID and any recent medications. If you’re taking manganese supplements or have recent exposure to manganese-containing products, inform your doctor.

What the Results Mean

Results are interpreted based on your overall health, symptoms, and medical history. High levels may suggest exposure or metabolic issues, while low levels might indicate deficiencies (though manganese is rarely deficient in healthy individuals). Your doctor will discuss findings in the context of your care plan.

Common Causes of Abnormal Results

Elevated manganese levels can result from occupational exposure, certain medications (e.g., some antibiotics or antacids), or liver/kidney dysfunction. Low levels are uncommon but may occur in rare genetic disorders or severe malnutrition. Chronic exposure to manganese (e.g., from industrial settings) can damage the nervous system over time.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum or plasma manganese level

Frequently asked questions

What questions might you have about this test?
This test is primarily used to diagnose or monitor conditions related to manganese toxicity or metabolic disorders. It’s not typically part of routine screening unless symptoms or risk factors are present.
How often should I get this test?
Frequency depends on your health status and risk factors. If you have a history of manganese exposure or related conditions, your doctor may recommend periodic monitoring. Otherwise, this test is usually ordered as needed for specific concerns.
Can I prepare for this test at home?
Yes, follow your doctor’s instructions for fasting or avoiding certain foods/drugs if specified. Avoid manganese-rich foods (e.g., nuts, chocolate) for 24 hours before testing if instructed. Bring a list of medications to your appointment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy