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Manganese in Serum or Plasma (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of manganese, a trace mineral, present in your blood. Manganese is important for bone health, metabolism, and nerve function, but high levels can indicate potential health risks.

Quick summary

["Understanding your manganese levels helps assess exposure risks or metabolic needs."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13645-7
Short code
Manganese Wat-mCnc
Synonyms
Manganese Wat-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like joint pain, nerve damage, or liver issues, or if you’ve been exposed to high levels of manganese (e.g., occupational hazards). It may also be checked in cases of suspected manganese toxicity or metabolic disorders.

What Does the Result Mean?

Results are not standardized across labs, so your provider will interpret them in the context of your health. Abnormally high levels may signal exposure or metabolic issues, while very low levels might indicate deficiencies (rare).

Common Causes of Abnormal Results

High manganese levels can result from occupational exposure (e.g., mining, welding), certain medications, or liver/kidney dysfunction. Low levels are uncommon but may occur with malabsorption or rare genetic conditions.

What Should You Expect During the Test?

A simple blood draw is typically used. You may feel slight discomfort, but it’s quick and safe. No special preparation is usually needed unless directed by your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Manganese Level

Frequently asked questions

Could high manganese levels harm me?
Yes, prolonged exposure to high manganese levels (e.g., occupational or environmental) may cause neurological symptoms like tremors, Parkinson-like features, or cognitive issues. Chronic low-level exposure may also pose risks.
What if my manganese level is low?
Low manganese levels are rare and usually not clinically significant unless accompanied by symptoms like fatigue or bone pain. Your provider may check other markers to assess overall mineral balance.
Do I need to avoid anything before this test?
No special precautions are needed, but avoid heavy exercise or stress before the blood draw if advised by your provider. Follow any general fasting instructions if your test requires it.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy