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Mannose-to-Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

This urine test compares mannose with creatinine to measure mannose excretion while accounting for differences in urine concentration.

Quick summary

["The result shows the relative amount of mannose being released in the urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74893-9
Short code
Mannose/Creat Ur-sRto
Synonyms
Mannose/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of mannose, a type of sugar, in your urine relative to the amount of creatinine, a waste product made by your muscles. The ratio helps account for how concentrated or dilute your urine is.

Why might I need this test?

A clinician may order this test when evaluating how your body processes carbohydrates or when a suspected disorder affects mannose metabolism. It is generally interpreted together with symptoms and other laboratory tests.

How is the test performed?

You provide a urine sample in the container specified by the healthcare provider or laboratory. The laboratory measures mannose and creatinine in the sample and calculates their ratio.

How do I prepare for the test?

No special preparation is usually required, but follow your clinician's instructions about when and how to collect the urine. If a timed collection is requested, record the start and end times and collect all urine during that period.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine mannose/creatinine ratio

Frequently asked questions

What does the urine mannose/creatinine ratio measure?
It measures the amount of mannose in urine compared with creatinine. Creatinine is used as a reference because its amount in urine varies with urine concentration.
Do I need to fast before this test?
Fasting is not generally required for a urine collection, but your clinician may give specific instructions. Follow any directions about collection timing, diet, or medication use.
Can this test be used to diagnose a condition on its own?
No. An abnormal result must be evaluated with medical history, symptoms, kidney function tests, and other relevant laboratory findings.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy