Skip to content

Total Serum/Plasma Electrophoresis (with Bromocresol Green or Bromocresol Purple Staining)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein types in your blood, including albumin and globulins, often used to diagnose conditions affecting protein balance.

Quick summary

["Helps identify protein disorders or abnormalities in blood protein composition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
39084-9
Short code
Marsh Elder IgE/IgE total %
Synonyms
Marsh Elder IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like multiple myeloma, amyloidosis, chronic liver disease, or other protein-related disorders. It can also help monitor treatment progress or detect subtle changes in protein levels that might not be picked up by other tests.

What to Expect During the Test

A small blood sample is drawn from a vein in your arm. The blood is then processed and analyzed to separate proteins based on their size and charge. Staining techniques (like bromocresol green or purple) highlight different protein bands for evaluation.

Common Conditions Evaluated

This test is particularly useful for identifying abnormal protein patterns, such as those seen in monoclonal gammopathies (e.g., multiple myeloma), hypoalbuminemia, or inflammatory conditions. It may also be used in screening for genetic disorders affecting protein synthesis.

How Results Are Interpreted

Results are typically expressed as percentages or relative amounts of each protein fraction (e.g., albumin, alpha-globulins, beta-globulins, gamma-globulins). Abnormal patterns may indicate specific conditions, but interpretation requires clinical correlation with symptoms and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test provides critical information about protein composition in your blood, which can reveal underlying disorders affecting protein metabolism. For example, elevated or abnormal bands may signal conditions like plasma cell dyscrasias (e.g., multiple myeloma) or chronic infections. Low albumin levels might indicate malnutrition, liver disease, or kidney problems. Always discuss results with your healthcare provider to understand their relevance to your health.

Short name

Total Protein Electrophoresis

Frequently asked questions

What does a total protein electrophoresis test measure?
It measures the types and amounts of proteins in your blood, including albumin and various globulins, often visualized as bands after separation by electrophoresis and staining.
Can this test detect cancer?
Yes, it can help identify certain cancers or cancer-like conditions (e.g., multiple myeloma) by showing abnormal protein patterns, such as a spike in monoclonal proteins.
How long does it take to get results from this test?
Results are typically available within 1–3 business days, depending on lab processing times and whether additional confirmatory tests are needed.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy