Maternal Serum/Plasma Biomarker Profile for Pregnancy-Related Screening (Composite Panel)

What This Test Measures

This test evaluates multiple substances in your blood that are critical during pregnancy. These may include markers for protein levels, hormone activity, and metabolic functions that support fetal growth and maternal health. Some tests may also check for genetic or chromosomal conditions.

Common Components of the Panel

While the exact tests vary by lab, this panel often includes measurements such as alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and other proteins or enzymes that reflect pregnancy-specific processes. Some labs may also assess glucose, lipids, or other biomarkers depending on clinical need.

Why It’s Done

Your healthcare provider may order this test to monitor your pregnancy’s progress, screen for conditions like Down syndrome or neural tube defects, or assess metabolic health (e.g., diabetes risk). It can also help detect maternal conditions like anemia or thyroid disorders that may impact pregnancy.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. The blood is processed to separate serum or plasma for testing. Avoid eating or drinking anything (except water) for 8–12 hours before the test if instructed.