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Metabolite and Retinol Erythrocyte Index (MREI) – Quantitative

Published: August 9, 2026Updated: August 16, 2026

This test measures a combination of metabolic markers and vitamin A levels in your blood, often used to assess nutritional status and metabolic health.

Quick summary

["Helps evaluate vitamin A stores and overall metabolic function in blood samples."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51635-1
Short code
Mat Retics #
Synonyms
Mat Retics #
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The MREI combines measurements of retinol (vitamin A) in your red blood cells and other metabolic substances. Retinol is a fat-soluble vitamin essential for vision, immune function, and cell growth. The test may also include related metabolites that reflect how your body processes nutrients.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms of vitamin A deficiency (such as night blindness or dry skin), suspected metabolic disorders, or if you’re undergoing treatment that could affect nutrient absorption.

Sample Preparation and Collection

A blood sample is drawn from a vein, typically in your arm. The sample is processed into either serum (after clotting) or plasma (using an anticoagulant). This test is usually performed on fresh or refrigerated samples within 24 hours of collection.

Common Reasons for Testing

Common indications include evaluating nutritional deficiencies, monitoring chronic conditions like liver disease or malabsorption syndromes, or assessing vitamin A status in patients with suspected metabolic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low MREI levels may indicate vitamin A deficiency or metabolic dysfunction, potentially leading to impaired vision, weakened immunity, or other systemic issues. Elevated levels could suggest liver disease, overconsumption of vitamin A supplements, or other metabolic abnormalities. Regular monitoring helps manage long-term health risks associated with these conditions.

Short name

MREI (Serum/Plasma)

Frequently asked questions

What does an abnormal MREI result mean?
An abnormal result may signal either a deficiency in vitamin A or related metabolic issues, but results alone aren’t diagnostic. Your provider will consider your symptoms, medical history, and other test results to determine the cause.
How often should I get this test?
Frequency depends on your health status. If you have a known condition like liver disease or malabsorption, your provider may recommend periodic testing. Otherwise, this test is rarely routine unless symptoms arise.
Can I take supplements before the test?
Yes, but discuss it with your provider first. Vitamin A supplements can affect results, so timing may need adjustment based on your specific needs.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy