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Serum or plasma measurement of total bilirubin concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood, a yellow pigment produced when red blood cells break down. It helps assess liver function and detect conditions like jaundice or bile duct blockages.

Quick summary

["Bilirubin levels can signal liver or bile system issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23234-8
Short code
M avium av Ab Bld Ql
Synonyms
M avium av Ab Bld Ql
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Bilirubin is a normal byproduct of red blood cell breakdown. When your liver processes it, healthy levels stay within a typical range. If levels rise, it may indicate problems like liver disease, gallbladder issues, or hemolysis (red blood cell destruction).

What to Expect Before the Test

You’ll likely have a simple blood draw from a vein in your arm. No special preparation is needed unless your doctor specifies otherwise. If you’re taking medications that affect liver function, mention them to your provider.

Common Conditions This Test Helps Diagnose

High bilirubin levels often point to jaundice (yellowing of skin/eyes), liver inflammation (hepatitis), bile duct obstructions, or inherited disorders like Gilbert’s syndrome. Low levels are less common but may signal rare conditions.

How Results Are Interpreted

Results are compared to your baseline or reference ranges provided by your lab. While exact values vary by lab, abnormal results trigger follow-up questions about symptoms, diet, or other health factors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Bilirubin’s Role in Health

Short name

Total bilirubin

Frequently asked questions

What causes elevated bilirubin?
Elevated bilirubin often stems from overproduction (e.g., anemia), impaired liver processing, or blocked bile flow. Symptoms like dark urine, pale stools, or fatigue may accompany high levels.
How often should I get this test?
Your doctor will determine frequency based on your health history. Routine checks may occur if you have liver-related conditions, recent infections, or symptoms like jaundice.
Does diet affect bilirubin levels?
Dietary factors like alcohol or certain medications can influence liver function indirectly, but bilirubin itself isn’t directly affected by food. Stick to your doctor’s advice regarding diet and medications.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy