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Serum or Plasma Creatinine Concentration (Qualitative or Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function check: creatinine levels help detect early kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23235-5
Short code
M avium av Ab Bld Ql Aggl
Synonyms
M avium av Ab Bld Ql Aggl
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
aggl
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Your Kidneys Matter

Kidneys filter waste and excess substances from your blood, including creatinine. When kidneys don’t work well, creatinine builds up, which can signal kidney damage or disease. This test is often used alongside other measures to monitor kidney health, especially in people with risk factors like diabetes or high blood pressure.

What to Expect During the Test

A blood sample is taken from a vein, usually in your arm. You may feel a small pinch, but it’s quick. No special preparation is needed unless your doctor instructs otherwise. The test may be done as part of a routine check or to investigate symptoms like fatigue, swelling, or changes in urine.

Common Uses for This Test

Doctors use creatinine levels to diagnose or monitor kidney disease, track progress of treatments, or check for kidney problems in people with conditions like diabetes or heart disease. It’s also part of a broader panel to evaluate overall health, especially in older adults or those with chronic illnesses.

Factors That Can Affect Results

Several factors can influence creatinine levels, including muscle mass (higher muscle = higher creatinine), dehydration, diet (especially protein intake), and certain medications. If you’ve had recent exercise, ate a high-protein meal, or are dehydrated, your results might be temporarily higher. Always discuss these with your doctor.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level (Serum/Plasma)

Frequently asked questions

How high or low are my creatinine levels compared to what’s expected for my age and health?
Creatinine levels alone aren’t diagnostic—they’re part of a picture. Your doctor will compare your results to your overall health, other tests (like blood pressure or urine tests), and symptoms. For example, consistently high levels may indicate kidney issues, while very low levels could signal muscle loss or liver/kidney problems. Always ask your doctor to interpret your specific results in context.
Can I eat or drink anything before this test?
No special diet or fasting is required for this test. However, if you’re taking medications that affect kidney function (like NSAIDs or certain blood pressure drugs), let your doctor know. Avoid excessive alcohol or high-protein meals 24 hours before testing, as they can temporarily alter results.
What if my test results are abnormal?
If your creatinine levels are outside the expected range, your doctor may recommend follow-up tests or adjustments to your treatment plan. For example, higher levels might prompt further kidney function tests, while lower levels could lead to investigations for conditions like malnutrition or liver disease. Always follow your doctor’s guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy