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Mutan Lectin Binding (MLB) Test for Bile Acid Analysis (24-hour urine)

Published: August 9, 2026Updated: August 16, 2026

This test measures specific bile acids in your urine over 24 hours to help assess how well your liver and bile ducts are processing fats and bile. It may be used to evaluate conditions affecting bile flow or metabolism.

Quick summary

["This test helps diagnose or monitor conditions linked to bile acid dysfunction or liver/bile duct issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
76068-6
Short code
MBL2 Mut Anl Bld/T
Synonyms
MBL2 Mut Anl Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like abdominal pain, unexplained weight loss, or signs of liver disease. It may also be used in research or specialized clinical studies evaluating bile acid metabolism.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period, typically starting after midnight on one day and ending midnight the next. Follow your provider’s instructions carefully to ensure accurate results. Avoid certain medications that could interfere with bile acid levels.

What Happens During the Test

No special preparation is needed beyond collecting urine in a sterile container. The sample is sent to a lab for analysis using specialized techniques to detect bile acids.

Possible Results and Interpretation

Results are compared to reference ranges for healthy individuals, though exact values may vary by lab. Abnormal patterns could indicate issues like bile duct blockages, liver disease, or metabolic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

24-Hour Urine Bile Acid Profile (MLB)

Frequently asked questions

What could cause abnormal results?
Abnormal bile acid levels may suggest conditions like primary biliary cholangitis, cystic fibrosis, or other metabolic disorders affecting bile production or transport. Your provider will discuss findings in relation to your symptoms and medical history.
How long will I need to wait for results?
Results typically take 2–5 business days, depending on lab processing times. Your provider will contact you once results are available.
Can I drink alcohol or take certain medications before this test?
Avoid alcohol and medications that may affect bile acid levels (e.g., some antibiotics or cholesterol medications) unless instructed otherwise by your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy