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Antibody to Neisseria meningitidis (Group B) – Immunoassay (CLIA)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies your immune system produces in response to *Neisseria meningitidis* Group B bacteria, which can cause serious infections like meningitis.

Quick summary

["Helps assess immune response to meningococcal Group B infection or vaccination."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101772-2
Short code
M canis DNA Spec Ql NAA+probe
Synonyms
M canis DNA Spec Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms of meningitis (e.g., severe headache, stiff neck, fever) or if you’ve been exposed to *N. meningitidis* Group B. It may also be used to monitor immune response after vaccination or in research settings.

What to Expect Before the Test

A blood sample is drawn from a vein in your arm. You may feel slight discomfort, but it usually lasts only a few minutes. No special preparation is needed.

How the Results Are Interpreted

Results are qualitative (positive/negative) and indicate whether detectable antibodies are present. High levels suggest prior exposure or vaccination response.

Possible Causes of Positive Results

A positive result may mean you’ve had prior infection, received the meningococcal vaccine, or are naturally developing immunity. False positives can occur rarely.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Meningitis B Antibody (IgG)

Frequently asked questions

What does a positive result mean?
A positive result suggests your body has recognized *N. meningitidis* Group B bacteria or received a vaccine containing these bacteria. This doesn’t mean you’re currently infected, but it confirms your immune system has responded.
No, this test alone cannot diagnose meningitis. It’s typically used alongside clinical evaluation and other tests (like lumbar puncture or culture) to assess exposure or immune response.
The most common side effect is mild bruising or soreness at the injection site. Rarely, there may be a slight swelling or redness. Most people tolerate the procedure without issues.
How soon will I get my results?
Results are usually available within 24–48 hours, depending on lab processing times. Your healthcare provider will discuss them with you during your follow-up visit.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy