C-reactive protein (CRP) with high-sensitivity measurement (serum/plasma)
This blood test measures a protein called C-reactive protein, which your body produces in response to inflammation. It helps assess low-level inflammation that may not be detected by other tests.
["High-sensitivity CRP helps track subtle inflammation, often used alongside other tests to monitor conditions like heart disease risk or autoimmune responses."]
Key facts at a glance
- LOINC
- 111285-3
- Short code
- M cap caprip Ab Msmt Ser
- Synonyms
- M cap caprip Ab Msmt Ser
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Doctors may order a high-sensitivity CRP test to evaluate your risk for heart disease, monitor chronic inflammatory conditions, or check for signs of infection or inflammation that aren’t easily detected with standard tests. It’s sometimes used in combination with other tests to guide treatment decisions.
How Is the Sample Collected?
A small amount of blood is drawn from a vein, usually in your arm. The blood is placed in a tube and sent to a lab for analysis. You may feel a brief pinch, but it’s typically over quickly. No special preparation is needed.
What Does the Test Measure?
High-sensitivity CRP measures very small amounts of CRP in your blood. CRP is a marker of inflammation, meaning it rises when your body responds to injury, infection, or other stressors. This test is particularly sensitive and can detect low levels of inflammation that might not be picked up by standard CRP tests.
What Might Affect Results?
Several factors can influence CRP levels, including recent illness, infection, injury, stress, certain medications (like steroids), or chronic conditions like arthritis or heart disease. Smoking, obesity, or poor diet may also affect results. It’s important to discuss your medical history and any recent activities with your healthcare provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
High-Sensitivity CRP (hs-CRP)
Frequently asked questions
How can this test help my healthcare provider?
What does a high or low CRP level mean?
Do I need to prepare for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy