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C-reactive protein (CRP) measured by high-sensitivity immunoassay

Published: August 9, 2026Updated: August 16, 2026

This blood test measures a protein produced by your liver in response to inflammation. It helps assess low-level inflammation that may not be detected by other tests.

Quick summary

["High CRP levels may signal subtle inflammation, useful for monitoring conditions like heart disease or autoimmune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23271-0
Short code
M cap caprip rRNA Spec Ql Probe
Synonyms
M cap caprip rRNA Spec Ql Probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

CRP is a marker of inflammation, often used to track conditions where inflammation plays a role—even when symptoms aren’t obvious. High-sensitivity CRP (hsCRP) is particularly sensitive and can detect mild inflammation that might otherwise go unnoticed.

How It Works

Your blood sample is tested using a specialized immunoassay method that detects tiny amounts of CRP. This test is designed to pick up very low levels of inflammation, which can be important for certain health checks.

What to Expect Before the Test

No special preparation is needed, but you may want to avoid strenuous activity or infections before the test, as these can temporarily raise CRP levels.

What the Results Mean

Results are reported in milligrams per liter (mg/L). While reference ranges vary by lab, higher-than-normal levels may indicate inflammation, infection, or other health concerns. Your doctor will interpret results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

hsCRP (high-sensitivity C-reactive protein)

Frequently asked questions

CRP is commonly used to monitor chronic inflammation in conditions like cardiovascular disease, rheumatoid arthritis, or after surgeries. It can also guide treatment decisions for conditions like heart disease or autoimmune disorders.
This test helps doctors track subtle changes in your body’s inflammatory response, even when symptoms aren’t present. It’s often used alongside other tests to provide a fuller picture of your health.
What does a high CRP level mean?
A high CRP level suggests inflammation is present in your body. It could be due to infection, injury, autoimmune conditions, or other health issues. Your doctor will discuss the results with you and may recommend further testing or adjustments to your treatment plan.
Can diet or exercise affect CRP levels?
Yes, lifestyle factors like diet, exercise, and stress can influence CRP levels. Eating a heart-healthy diet, staying active, and managing stress may help lower CRP levels over time. Always follow your doctor’s advice regarding lifestyle changes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy