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C-reactive protein (CRP) concentration, plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein in your blood plasma, a protein produced by the liver that rises in response to inflammation or infection.

Quick summary

["CRP helps doctors assess inflammation, guiding treatment for conditions like infections, autoimmune diseases, or heart disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
76588-3
Short code
M catarr g1b XXX.tiss NAA+probe
Synonyms
M catarr g1b XXX.tiss NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for signs of inflammation, monitor chronic conditions like arthritis or heart disease, or evaluate responses to treatments. It can also help diagnose infections or identify risks for conditions like heart attacks or stroke.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein. Wear comfortable clothing and bring any medications you’re currently taking.

How the Test Works

A healthcare professional will take a blood sample from a vein in your arm. The blood is then processed to separate plasma, where CRP levels are measured using an immunoassay method to detect and quantify the protein.

What the Results Mean

Results are typically reported in milligrams per liter (mg/L). Higher than normal levels may indicate inflammation, infection, or an underlying health issue. Your doctor will interpret results in the context of your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP is a key marker for inflammation. Elevated levels often signal infections, autoimmune disorders, or other inflammatory conditions. It’s also used to monitor disease activity or response to treatment in conditions like rheumatoid arthritis or cardiovascular disease. While not specific to a single cause, CRP helps guide decisions about further testing or treatment adjustments.

Short name

CRP (Plasma)

Frequently asked questions

What causes CRP levels to be higher than usual?
CRP can rise due to infections (like pneumonia or urinary tract infections), injuries, surgeries, or autoimmune diseases (like lupus or rheumatoid arthritis). Stress, smoking, or certain medications may also influence levels.
How often should I get this test?
Your doctor will determine the frequency based on your health needs. Some people get it annually to monitor chronic conditions, while others may need it more often if symptoms or treatment changes occur.
Can diet or lifestyle affect CRP levels?
Yes—diet high in processed foods, sugar, or unhealthy fats may increase inflammation. Regular exercise, a balanced diet, and avoiding smoking can help lower CRP levels and support overall health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy