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C-reactive protein (CRP) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body. It helps doctors assess whether you have an inflammatory condition or infection.

Quick summary

["CRP helps track inflammation, guiding treatment decisions for infections, autoimmune diseases, or other conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94373-8
Short code
M catarrhalis DNA Lower Resp Ql NAA+prb
Synonyms
M catarrhalis DNA Lower Resp Ql NAA+prb
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why CRP Matters in Your Health

CRP is a marker for inflammation, which is your body’s way of responding to injury, infection, or illness. High levels may signal conditions like infections, autoimmune diseases (such as rheumatoid arthritis), or other inflammatory processes. Your doctor may order this test to monitor your condition, check for hidden inflammation, or guide treatment adjustments.

When This Test Is Ordered

Doctors often request CRP testing if you have symptoms like fever, joint pain, or unexplained fatigue. It may also be used to evaluate conditions like heart disease, kidney disease, or to monitor chronic illnesses like lupus or rheumatoid arthritis. Some doctors check CRP levels before surgeries or during follow-ups for ongoing health concerns.

What to Expect Before the Test

No special preparation is needed for most CRP tests. If your blood is drawn, you may have a small needle inserted into your arm. If you’re having a urine test, you’ll likely collect a sample at home or in a clinic. Always follow your healthcare provider’s instructions for timing (e.g., fasting may not apply for CRP).

What the Results Mean

Results are usually reported in milligrams per liter (mg/L). A normal range isn’t always the same for everyone, as it can vary by lab and individual health. High CRP levels may indicate inflammation, while very low levels might suggest no active inflammation. Your doctor will interpret results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CRP

Frequently asked questions

How often should I get this test?
CRP testing frequency depends on your health condition. For example, people with heart disease or autoimmune diseases may get CRP checked regularly (e.g., every few months) to monitor inflammation. If you have no known conditions, your doctor may order it only if symptoms suggest inflammation or infection.
Can CRP levels change with diet or exercise?
Yes, lifestyle factors can influence CRP levels. Regular exercise and a healthy diet may help lower inflammation, but CRP is also affected by stress, sleep, and certain medications. Avoiding smoking and managing weight can also support lower CRP levels.
Is CRP the same as a white blood cell count?
No, CRP and white blood cell counts serve different purposes. CRP measures inflammation specifically, while white blood cell counts track the number of immune cells. Both tests can be used together to get a clearer picture of your health, especially in infections or inflammatory diseases.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy