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C-reactive protein (CRP) by nephelometry (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This blood test measures the level of C-reactive protein, a protein produced by your liver in response to inflammation in your body.

Quick summary

["CRP helps track inflammation, often used to monitor conditions like infections, autoimmune diseases, or after surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92965-3
Short code
M catarrhalis DNA Spt NAA+non-prb-NCncRng
Synonyms
M catarrhalis DNA Spt NAA+non-prb-NCncRng
Category
chemistry
Sample
sputum
Container
Sterile sputum container
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
CPT
85610
SNOMED
396252006
Specimen volume
3-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for signs of inflammation, monitor chronic conditions like rheumatoid arthritis or lupus, evaluate infections, or assess how your body is responding to treatment for certain illnesses.

What Does a High or Low Level Mean?

Elevated CRP levels often indicate inflammation, infections, or other health issues. Very low levels may suggest no active inflammation, but they can also occur in certain genetic conditions or with certain medications.

Sample Collection and Preparation

A blood sample is taken from a vein in your arm. The blood is sent to a lab where it is processed into serum or plasma for testing. No special preparation is needed, but you may be asked to fast for a few hours before the test if instructed by your provider.

What to Expect During the Test

The process is quick and typically painless. You may feel a slight pinch when the needle is inserted, but most people tolerate it well. You can usually resume normal activities immediately after.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: sputum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP is a marker for inflammation and is used broadly in medicine to guide treatment decisions, monitor disease progression, and assess treatment effectiveness. It can help identify underlying causes of symptoms like fever, joint pain, or fatigue that may not have a clear diagnosis otherwise.

Short name

CRP (Serum/Plasma)

Frequently asked questions

How often should I get this test?
The frequency depends on your health condition and treatment plan. Your healthcare provider will determine how often you need this test based on your specific situation, such as whether you have a chronic illness or are recovering from an illness.
What are the typical reference ranges?
Reference ranges can vary by lab and individual health status. Typically, lower levels (near zero) suggest minimal inflammation, while higher levels may indicate active inflammation or infection. Your provider will interpret the results in the context of your overall health.
Can I eat or drink before this test?
Most commonly, you may be asked to fast for a few hours before the test, but always follow your healthcare provider’s instructions. If they do not specify, you can usually eat and drink normally.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy