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Fetal Hemoglobin Concentration (Serum or Plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of fetal hemoglobin, a type of hemoglobin found in fetal red blood cells, which may be present in maternal blood under certain conditions.

Quick summary

["Assessing fetal hemoglobin helps evaluate potential blood-related conditions in pregnancy or blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
62243-1
Short code
MCH RBC Fetus Qn Auto
Synonyms
MCH RBC Fetus Qn Auto
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated-count
CPT
85041
SNOMED
900000000000003001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to check for conditions like fetal hemoglobin disorders, hemolytic diseases in newborns, or to monitor certain blood-related conditions in pregnant individuals. It can also be used in research or specialized clinical scenarios.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into a vein in your arm to draw a blood sample. If you’re pregnant, your healthcare provider will ensure it’s done safely.

What the Test Results Mean

Results are compared to expected ranges for fetal hemoglobin in maternal blood. Abnormal levels may indicate underlying health concerns that need further evaluation by a healthcare provider.

Common Reasons for Testing

This test is often used in prenatal care to screen for conditions affecting fetal development, in newborns to diagnose hemolytic diseases, or in research studies involving fetal hemoglobin.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Fetal hemoglobin can be elevated in conditions like hydrops fetalis (a severe fetal condition) or certain genetic disorders. Low levels may suggest maternal-fetal blood incompatibility or other blood disorders. Always discuss results with your healthcare provider.

Short name

Fetal Hb (Serum/Plasma)

Frequently asked questions

What is fetal hemoglobin and why is it measured in maternal blood?
Fetal hemoglobin is a protein in red blood cells that carries oxygen in fetal circulation. In rare cases, it can appear in maternal blood due to conditions like fetal-maternal hemorrhage or certain blood disorders. Measuring it helps diagnose or monitor these conditions.
How is this test different from a standard hemoglobin test?
This test specifically focuses on fetal hemoglobin, which is distinct from adult hemoglobin. Standard hemoglobin tests measure total hemoglobin, not its fetal form. Your provider will clarify the purpose of this specific test.
Can this test be done during pregnancy without risk?
Yes, if performed by a trained healthcare professional, this blood test is generally safe during pregnancy. Blood draws are standard in prenatal care and are monitored closely to ensure safety.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy