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Mass concentration of copper in plasma (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of copper present in your blood plasma, often checked to evaluate copper metabolism or identify potential copper toxicity.

Quick summary

["Your blood copper levels help doctors diagnose or monitor conditions like Wilson’s disease or copper overload."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78852-1
Short code
m-CPP Bld-mCnc
Synonyms
m-CPP Bld-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like nausea, vomiting, or neurological issues that could relate to copper imbalance. It’s also used in research or specialized clinical settings to assess copper metabolism in certain genetic conditions or after exposure to high copper levels (e.g., from medications or environmental sources).

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw if your test involves fasting-related interpretation. Wear a comfortable shirt for easy access to your arm. Bring any medications or supplements you’re taking, as they can sometimes affect results.

What Happens During the Test

A healthcare professional will insert a small needle into your arm to draw a blood sample. The process is quick and typically causes only minor discomfort. The blood is then sent to a lab for analysis using specialized techniques to measure copper concentration accurately.

What the Results Mean

Results are compared to standard reference ranges for healthy adults, though exact values can vary by lab. High levels may suggest copper toxicity or certain genetic disorders, while low levels could indicate malabsorption or liver issues. Your doctor will discuss findings in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Copper Level (Mass Concentration)

Frequently asked questions

What causes copper levels to be high?
High copper levels can result from genetic disorders like Wilson’s disease, excessive intake of copper supplements or medications, liver disease, or certain medications (e.g., some antibiotics or antacids). Environmental exposure to high copper levels (e.g., from industrial settings) may also contribute. Always discuss any recent changes in medications or supplements with your doctor.
What symptoms might indicate abnormal copper levels?
Symptoms of high copper levels may include nausea, vomiting, abdominal pain, neurological issues (e.g., tremors, weakness), or liver problems (e.g., jaundice). Symptoms of low copper levels might include fatigue, hair loss, or weakened immune function. However, many people with abnormal copper levels have no symptoms at all. Your doctor will evaluate your test results alongside your medical history and symptoms.
Does diet affect copper levels?
Dietary sources of copper (e.g., organ meats, shellfish, nuts, seeds) can influence copper levels, but the impact is usually small compared to genetic or medical factors. Certain foods or supplements may interact with copper metabolism, so it’s best to avoid excessive copper intake unless advised by your doctor. Always follow your healthcare provider’s guidance on dietary restrictions or supplements.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy